Tardive Dyskinesia is most commonly associated with long-term use of certain medications, particularly antipsychotic medications used to manage psychiatric conditions such as schizophrenia, bipolar disorder, and major depressive disorder. These medications have a higher risk of developing TD. Those taking second-generation (atypical) antipsychotics have a lower risk, but TD can still occur with prolonged use.
TD may develop after months or years of antipsychotic use, and sometimes even after stopping the medication. Regular screenings for movement disorders should be conducted, especially for individuals on long-term treatment.
TD can negatively impact quality of life, self-esteem, and social functioning, making early detection and management critical.